ESM231
1 / 115
One of these scientists prepared a systematic correlation between the chemical and biological properties of poisons of his time
2 / 115
Inhaled benzene is readily absorbed by the blood from which it is taken up by
3 / 115
Ozone can cause all but one of the following effects :
4 / 115
Which of these statements is not true of doseresponse relationship ?
5 / 115
Which of these is not a rodenticides?
6 / 115
Alcohols can lead to all but one of the following effects
7 / 115
Berylliosis a condition manifested by lung fibrosis and phenumonitis toxicity of the element
8 / 115
s the stage in which the neoplastic cells become a malignant tumour
9 / 115
The rate and extent of absorption of hydrophobic chemicals depends on all but one of these
10 / 115
Many pesticides in use have different modes of action and levels of
11 / 115
Nitrite can convert haemoglobin to
12 / 115
One of these is not true of nicotine.
13 / 115
Poisonous plants and are extracted for hunting and warfare
14 / 115
All but one of these defines toxicology:
15 / 115
Ingestion of_____can caused black sore syndrome in Turkey
16 / 115
The rate of extent of absorption of hydrophobic chemicals depends of these factors excep
17 / 115
All but one of these is true of active transport
18 / 115
Acetylcholine, a major neurotransmitterin animals is normallyrapidly deactivated by an enzyme called
19 / 115
Which of these events occurred in the 17th Century?
20 / 115
_________ is a widely used colourless gas that acts as an anesthetic to animals and is toxic to plants
21 / 115
Which of the following is the basic mechanism of action of insecticides?
22 / 115
Which of these is not true of DDT?
23 / 115
refers to a site of action other than the point of contact and presupposes that absorption has taken place.
24 / 115
is a metal which is widely used in industries, in alloys, in plating, in batteries and in the pigment in inks, paints, plastics, rubber and enamel
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means that the action takes place at the point or area of contact
26 / 115
Ludwig Rehn reported elevated incidences of bladder cancer in dye workers exposed to chemicals extracted from
27 / 115
_______ = Concentration x Exposure
28 / 115
has been known to be a poisonous compound for centuries
29 / 115
The micro-organisms in the sediments at the bottom bio-transformed the organic mercury ions methyl and ___________ mercury
30 / 115
The micro-organisms in the sediments at the bottom bio-transformed the organic mercury ions methyl and mercury
31 / 115
The historical development of toxicology began with____dwellers
32 / 115
Chemical species that cause birth defects are known as
33 / 115
__is the unrestrained, malignant proliferation of somatic cell
34 / 115
One of these can be classified as a chronic illness
35 / 115
Ingestion of __can cause black sore syndrome in Turkey
36 / 115
Which of these substances caused the disease, Minamata in Japan
37 / 115
Which conjugation reaction decreases, instead of increases, water solubility?
38 / 115
One of these methods of transportation through membranes does not involve specialized transport
39 / 115
is term will be used in contrast to acute exposure and it is of long duration
40 / 115
The historical development of toxicology began with _dwellers
41 / 115
Elemental mercury may be absorbed by biological system as a
42 / 115
42. The four routes of entry are:
43 / 115
Lead and most of the heavy metals have effect on the (PNS) or the (CNS)
44 / 115
Which of these statements is not true of the enzymes Cytochrome PN450
45 / 115
Pyrethroids fall into two categories based on their acute
46 / 115
The toxicological properties of _________ are very similar to those of ethylene
47 / 115
__________ has been known to be a poisonous compound for centuries
48 / 115
Hexachlorobezene studies in rats also provide evidence of
49 / 115
During the Phase I reactions an OH group is attached to benzene to change it to
50 / 115
One of these substances can easily be absorbed by the skin:
51 / 115
_________ is a metal which is widely used in industries, in alloys, in plating, in batteries and in the pigment in inks, paints, plastics, rubber and enamel
52 / 115
The stage in which the cancerous cells become a malignant tumour during the carcinogenic process is known as the
53 / 115
All but one of these are groups of insecticides
54 / 115
Which of these is NOT true of Paraquat
55 / 115
Which of these statements is NOT true of Rotenone ?
56 / 115
The primary risk associated with 2,4-D and 2,4,5-T was due to the presence small amounts of dioxin
57 / 115
“All things are poison and nothing is without poison; only the dose makes a thing a poison “ is a statement credited to:
58 / 115
59 / 115
Pesticides are chemicals that are use to kill
60 / 115
___________ is a metalloid which forms a number of toxic compounds
61 / 115
Dose-response relationship is a major concept of
62 / 115
What does NOEL stand for?
63 / 115
One of these areas of toxicology involves toxicologists with specialised knowledge of law working with pathologist to establish cases
64 / 115
65 / 115
Depression of the system will lower resistance to infectious disease and facilitate the development of
66 / 115
Which of these insecticides can be categorised as High toxic potential insecticide?
67 / 115
68 / 115
Which of these pesticides mimics the action of Acetylcholine
69 / 115
When a toxic effect occurs at the point or area of contact of the toxin, what type of effect is it said to have?
70 / 115
the outer most corny layer of the skin plays an important role in determining the permeability of this layer
71 / 115
Which of these events did not occur in the 19th Century
72 / 115
Pyrethroids that have Peripherial CNS effects are known as
73 / 115
_____is the unrestrained, malignant proliferation of somatic cell
74 / 115
The rate of extent of absorbtion of hydrophobic chemicals depends of these factors except
75 / 115
Acetylene is a colourless gas with a odour
76 / 115
Acute toxicity generally very low in
77 / 115
What term is used to indicate the ability of a cancer to invade other parts of the body and produce secondary tumours
78 / 115
Ozone irritates the eyes, upper respiratory system and
79 / 115
The involved as protective covering against a hostile environment and is relectively impermeable to many chemical
80 / 115
81 / 115
The toxicological properties of are very similar to those of ethylene
82 / 115
Phase II reaction are also known as
83 / 115
is a widely used colourless gas that acts as an anesthetic to animals and is toxic to plants
84 / 115
Toxicants can cause _which is the impairment of the body's natural defense mechanisms
85 / 115
85. DDT is a____ pesticide
86 / 115
One of these substances is a waste from leather products manufacturing industries
87 / 115
Lead and most of the heavy metals have __________ effect on the (PNS) or the (CNS)
88 / 115
A mutated cells does not necessarily form a
89 / 115
The concept that at extremely low dose, a given substance may be nontoxic and even beneficial while at intermediate dose, it may be toxic is
90 / 115
An exposure which would be relatively harmless unless repeated over a long period of time
91 / 115
Fungicides have the potential to be __based on their mutagenic activity
92 / 115
The toxicological property of _are very similar to ethylene
93 / 115
Toxicology integrates with all but one of these fields;
94 / 115
refers to a single exposure of duration measure in second minutes or hours
95 / 115
One of these substances can cause spontaneous abortion when inhaled:
96 / 115
The inhalation of air containing benzene can lead to the following progressive effects:
97 / 115
Which of these is NOT a symptom associated with back sore syndrome
98 / 115
One of these substances is not colourless.
99 / 115
Exposure to n-hexane and cyclohexane result in loss of myelin and degeneration of
100 / 115
One of these is not a constituent of Bordeaux mixture
101 / 115
Following the WHO Recommended Classification of Pesticides by hazard ,slightly hazardous are in CLASS
102 / 115
One of these definitions is known as "the traditional definition of toxicology"
103 / 115
104 / 115
104. s used to treat seed grain
105 / 115
One of these is not of importance in the conduct of risk assessments.
106 / 115
is measured by octanol:- water partition coefficient in a separatory funnel
107 / 115
One of these is not a heavy metal
108 / 115
Which of these statements is NOT true of synthetic pyrethroids ?
109 / 115
is a metalloid which forms a number of toxic compounds
110 / 115
The alkylation and arylaton of to cause motations is part of the toxicodynamic phase
111 / 115
Exposure to Toluene may lead to one of the following effects:
112 / 115
Organic mercury such as, methylmecury, is extremely toxic mainly affecting the central nervous system in Japan caused a disease known as
113 / 115
are the suspended liquid droplets generated by condensation from the gaseous to the liquid state.
114 / 115
_________ refers to a single exposure of duration measure in second minutes or hours
115 / 115
Absorption through the skin is promoted by all these except
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