ESM231

__is the unrestrained,
malignant proliferation of
somatic cell

One of these substances
can cause spontaneous
abortion when inhaled:

One of these substances is
a waste from leather
products manufacturing
industries

Acetylene is a colourless
gas with a
odour

_________ is a metal which
is widely used in industries,
in alloys, in plating, in
batteries and in the pigment
in inks, paints, plastics,
rubber and enamel

Acute toxicity generally very
low in

One of these is not of
importance in the conduct
of risk assessments.

Pyrethroids fall into two
categories based on their
acute

All but one of these are
groups of insecticides

_________ refers to a
single exposure of duration
measure in second minutes
or hours

Many pesticides in use
have different modes of
action and levels of

the outer most corny layer
of the skin plays an
important role in
determining the
permeability of this layer

Phase II reaction are also
known as

One of these is not a heavy
metal

Ludwig Rehn reported
elevated incidences of
bladder cancer in dye
workers exposed to
chemicals extracted from

Berylliosis a condition
manifested by lung fibrosis
and phenumonitis toxicity of
the element

Which of these events did
not occur in the 19th
Century

The historical development
of toxicology began
with____dwellers

Pyrethroids that have
Peripherial CNS effects are
known as

Exposure to Toluene may
lead to one of the following
effects:

Which of these substances
caused the disease,
Minamata in Japan

Which of these statements
is NOT true of Rotenone ?

__________ has been
known to be a poisonous
compound for centuries

When a toxic effect occurs
at the point or area of
contact of the toxin, what
type of effect is it said to
have?

Which of these events
occurred in the 17th
Century?

Ozone can cause all but
one of the following effects :

27. s used to treat seed grain

28. The four routes of entry are:

Dose-response relationship
is a major concept of

One of these areas of
toxicology involves
toxicologists with
specialised knowledge of
law working with pathologist
to establish cases

What term is used to
indicate the ability of a
cancer to invade other parts
of the body and produce
secondary tumours

The primary risk associated
with 2,4-D and 2,4,5-T was
due to the presence small
amounts of dioxin

refers to a site of action
other than the point of
contact and presupposes
that absorption has taken
place.

Many pesticides in use
have different modes of
action and levels of

has been known to be a
poisonous compound for
centuries

Absorption through the skin
is promoted by all these
except

The concept that at
extremely low dose, a given
substance may be nontoxic and even beneficial
while at intermediate dose,
it may be toxic is

Inhaled benzene is readily
absorbed by the blood from
which it is taken up by

The rate of extent of
absorption of hydrophobic
chemicals depends of these
factors excep

Depression of the system
will lower resistance to
infectious disease and
facilitate the development
of

___________ is a metalloid
which forms a number of
toxic compounds

Poisonous plants and
are extracted for hunting
and warfare

Toxicants can cause
_which is the impairment of
the body's natural defense
mechanisms

Which conjugation reaction
decreases, instead of
increases, water solubility?

_________ is a widely used
colourless gas that acts as
an anesthetic to animals
and is toxic to plants

Which of these is not true of
DDT?

Acetylcholine, a major
neurotransmitterin animals
is normallyrapidly
deactivated by an enzyme
called

One of these can be
classified as a chronic
illness

The alkylation and arylaton
of
to cause motations is part
of the toxicodynamic phase

The rate and extent of
absorption of hydrophobic
chemicals depends on all
but one of these

are the suspended liquid
droplets generated by
condensation from the
gaseous to the liquid state.

Nitrite can convert
haemoglobin to

Lead and most of the heavy
metals have
effect on the (PNS) or the
(CNS)

The micro-organisms in the
sediments at the bottom
bio-transformed the organic
mercury ions methyl and
___________ mercury

One of these definitions is
known as "the traditional
definition of toxicology"

Lead and most of the heavy
metals have __________
effect on the (PNS) or the
(CNS)

Following the WHO
Recommended
Classification of Pesticides
by hazard ,slightly
hazardous are in CLASS

refers to a single exposure
of duration measure in
second minutes or hours

is a metal which is widely
used in industries, in alloys,
in plating, in batteries and
in the pigment in inks,
paints, plastics, rubber and
enamel

One of these methods of
transportation through
membranes does not
involve specialized
transport

The
involved as protective
covering against a hostile
environment and is
relectively impermeable to
many chemical

Chemical species that
cause birth defects are
known as

s the stage in which the
neoplastic cells become a
malignant tumour

Which of these is not a
rodenticides?

Which of these statements
is NOT true of synthetic
pyrethroids ?

Pyrethroids fall into two
categories based on their
acute

_______ = Concentration x
Exposure

One of these substances is
not colourless.

A mutated cells does not
necessarily form a

Which of these pesticides
mimics the action of
Acetylcholine

Which of these insecticides
can be categorised as High
toxic potential insecticide?

is a metalloid which forms a
number of toxic compounds

_____is the unrestrained,
malignant proliferation of
somatic cell

Alcohols can lead to all but
one of the following effects

Fungicides have the
potential to be
__based on their mutagenic
activity

is term will be used in
contrast to acute exposure
and it is of long duration

means that the action takes
place at the point or area of
contact

The historical development
of toxicology began with
_dwellers

An exposure which would
be relatively harmless
unless repeated over a long
period of time

80. DDT is a____ pesticide

One of these substances
can easily be absorbed by
the skin:

Ozone can cause all but
one of the following effects :

“All things are poison and
nothing is without poison;
only the dose makes a
thing a poison “ is a
statement credited to:

is measured by octanol:-
water partition coefficient in
a separatory funnel

Acetylcholine, a major
neurotransmitterin animals
is normallyrapidly
deactivated by an enzyme
called

Which of the following is the
basic mechanism of action
of insecticides?

Ozone irritates the eyes,
upper respiratory system
and

All but one of these defines
toxicology:

Organic mercury such as,
methylmecury, is extremely
toxic mainly affecting the
central nervous system in
Japan caused a disease
known as

The toxicological properties
of _________ are very
similar to those of ethylene

The toxicological property
of
_are very similar to
ethylene

is a widely used colourless
gas that acts as an
anesthetic to animals and is
toxic to plants

What does NOEL stand
for?

Pesticides are chemicals
that are use to kill

Which of these statements
is not true of doseresponse relationship ?

Toxicology integrates with
all but one of these fields;

Hexachlorobezene studies
in rats also provide
evidence of

Which of these is NOT true
of Paraquat

Exposure to n-hexane and
cyclohexane result in loss
of myelin and degeneration
of

Which of these statements
is not true of the enzymes
Cytochrome PN450

Ingestion of_____can
caused black sore
syndrome in Turkey

During the Phase I
reactions an OH group is
attached to benzene to
change it to

One of these is not a
constituent of Bordeaux
mixture

The rate of extent of
absorbtion of hydrophobic
chemicals depends of these
factors except

Elemental mercury may be
absorbed by biological
system as a

The inhalation of air
containing benzene can
lead to the following
progressive effects:

The micro-organisms in the
sediments at the bottom
bio-transformed the organic
mercury ions methyl and
mercury

One of these is not true of
nicotine.

One of these scientists
prepared a systematic
correlation between the
chemical and biological
properties of poisons of his
time

Which of these is NOT a
symptom associated with
back sore syndrome

The toxicological properties
of
are very similar to those of
ethylene

The stage in which the
cancerous cells become a
malignant tumour during
the carcinogenic process is
known as the

Ingestion of
__can cause black sore
syndrome in Turkey

Pesticides are chemicals
that are use to kill

All but one of these is true
of active transport